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20 May 2019

#China, #Influenza [#H1N1pdm09, #H3N2, B, #H7N9] Weekly #Report - Wk 19 ‘19 (CNIC, May 20 ‘19)


Title:

#China, #Influenza [#H1N1pdm09, #H3N2, B, #H7N9] Weekly #Report - Wk 19 ‘19.

Subject:

Seasonal Influenza, current epidemiological situation in China.

Source:

National Influenza Centre (CNIC), PR of China, full page: (LINK).

Code:

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Download:China flu report 1919.pdf 

(All data are preliminary and may change as more reports are received)


Summary

  • During week 19, influenza activity level continued to decrease in mainland China with B-Victoria lineage virus most frequently detected, followed by influenza A(H3N2) and very few detections of influenza A(H1N1)pdm09 and B-Yamagata viruses.
  • Among influenza viruses antigenically characterized by CNIC since October 1st, 2018:
    • 1763 (97.3%) influenza A(H1N1)pdm09 viruses were characterized as A/Michigan/45/2015-like;
    • 241 (75.5%) influenza A(H3N2) viruses were characterized as A/Singapore/INFIMH-16-0019/2016 (EGG)-like,
    • 297 (93.1%) influenza A(H3N2) viruses were characterized as A/Singapore/INFIMH-16-0019/2016 (CELL)-like;
    • 64 (27.8%) influenza B/Victoria viruses were characterized as B/Colorado/06/2017-like;
    • 45 (100.0%) influenza B/Yamagata viruses were characterized as B/Phuket/3073/2013-like.
  • Among the influenza viruses tested by CNIC for antiviral resistance analysis since October 1st, 2018:
    • all influenza A(H1N1)pdm09 and A(H3N2) viruses were resistant to amantadine;
    • All influenza A(H3N2) and B viruses were sensitive to neuraminidase inhibitors.
    • All but 9 influenza A(H1N1)pdm09 were sensitive to neuraminidase inhibitors.


Surveillance of outpatient or emergency visits for Influenza-like Illness (ILI)

  • During week 19, the percentage of outpatient or emergency visits for ILI (ILI %) at national sentinel hospitals in southern provinces was 4.0%, lower than the last week (4.5%), higherthan the same week of 2016-2018 (3.6%, 3.2% and 3.7%). (Figure 1)
  • During week 19, ILI% at national sentinel hospitals in northern provinces was 2.6%, lower than the last week (3.2%), same as the same week of 2017 (2.6%), higher than the same week of 2016 and 2018 (both 2.3%). (Figure 2)

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Figure 1. Percentage of Visits for ILI at Sentinel Hospitalsin South China (2016-2020)

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Figure 2. Percentage of Visits for ILI at Sentinel Hospitals in North China (2016-2020)

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Virologic Surveillance

  • During week 19, influenza network laboratories tested 4866 specimens, of which 993(20.4%) were positive for influenza, influenza A and influenza B viruses were 119(12.0%) and 874(88.0%), respectively (Table 1).
  • During week 19, the percentage of specimens that were tested positive for influenza in south China was 21.0%, which was slightly higher than the previous week (20.1%)(Figure 3).
  • During week 19, the percentage of specimens that were tested positive for influenza in north China was 18.8%, which was lower than the previous week (25.8%). (Figure 4).

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Table 1 - Laboratory Detections of ILI Specimens (Week 19, 2019)

[Week 19: South China - North China – Total]

  • No. of specimens tested – 3618 – 1248 – 4866
    • No. of positive specimens (%) - 759(21.0%) - 234(18.8%) - 993(20.4%)
      • Influenza A - 92(12.1%) - 27(11.5%) - 119(12.0%)
        • A(H3N2) - 76(82.6%) - 25(92.6%) - 101(84.9%)
        • A(H1N1)pdm09 - 16(17.4%) - 2(7.4%) - 18(15.1%)
        • A (subtype not determined) - 0(0) - 0(0) - 0(0)
      • Influenza B - 667(87.9%) - 207(88.5%) - 874(88.0%)
        • B (lineage not determined) - 11(1.6%) - 2(1.0%) - 13(1.5%)
        • Victoria - 652(97.8%) - 203(98.1%) - 855(97.8%)
        • Yamagata - 4(0.6%) - 2(1.0%) - 6(0.7%)

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Figure 3. Influenza Positive Tests Reported by Southern Network Laboratories (Week 14, 2018–Week 19, 2019)

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Note: Analysis in this part was based on the test results of network laboratories. If it were not consistent with the results of CNIC confirmation, the results of CNIC confirmation were used.

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Figure 4. Influenza Positive Tests Reported by Northern Network Laboratories (Week 14, 2018–Week 19, 2019)

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Note: Analysis in this part was based on the result of network laboratories. If it were not consistent with the results of CNIC confirmation, the results of CNIC confirmation were used.

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Outbreak Surveillance

  • During week 19 (May 6th 2019 –May 12th 2019), there were forty outbreaks reported nationwide, fifteen of them were B(Victoria), eight of them were B (lineage not determined), seven of them were A(H3N2), one of them was B(Yamagata), two of them were mixed, six of them had not been obtained the results, one of them was negative for influenza.

(…)


H7N9 Case Report

  • During week 19, no new human infection with novel reassortant influenza A(H7N9) virus was reported.


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Keywords: China; Updates; Seasonal Influenza; Avian Influenza; Influenza B; H1N1pdm09; H3N2; H7N9.

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