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6 Oct 2016

#Zika #global #situation #report, 6 October 2016 (@WHO, summary)

 

Title: #Zika #global #situation #report, 6 October 2016.

Subject: Zika Virus Infection and Related Complications, weekly global update.

Source: World Health Organization (WHO), full page: (LINK). Summary.

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Zika situation report, 6 October 2016

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Zika virus, Microcephaly and Guillain-BarrĂ© syndrome: |-- Read the full situation report –|

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Key updates

  • Countries and territories reporting mosquito-borne Zika virus infections for the first time in the past week:
    • None
    • The investigation by the Ministry of Public Health of Thailand confirmed 2 cases of Zika-related microcephaly on 30 September 2016.
      • This is the first time that Zika-related microcephaly cases have been confirmed in Southeast Asia.
      • The mothers reported no travel history to areas outside of Thailand.
  • Countries and territories reporting microcephaly and other central nervous system (CNS) malformations potentially associated with Zika virus infection for the first time in the past week:
    • Thailand
  • Countries and territories reporting Guillain-BarrĂ© syndrome (GBS) cases associated with Zika virus infection for the first time in the past week:
    • Mexico

 

Analysis

  • Overall, the global risk assessment has not changed.
  • The reporting of 2 locally acquired cases of Zika-related microcephaly in Thailand confirms that this complication may occur in Southeast Asia.
    • Since attempts at genetic sequencing of this virus were unsuccessful, it is not known whether the mothers were infected with a strain of virus related to those previously isolated in Southeast Asia, or if there has instead been transmission of a virus strain imported from the Americas.
    • A programme for active surveillance of microcephaly was established in February 2016 in Thailand, and is in the process of being integrated into routine arrangements for surveillance of birth defects.
    • If a Zika virus strain previously circulating in Southeast Asia was found to be linked to microcephaly or other complications, it would have significant impact on the global risk assessment, as it would demonstrate that Zika-associated complications are not limited to the “Asian” strain circulating since 2013 in the Western Pacific Region, the Region of the Americas, and Cabo Verde.
  • The risk of Zika-associated complications in countries thought to be endemic for Zika virus remains largely unknown, due both to uncertainty about the risk associated with different Zika strains, and due to uncertainty about population immunity in these endemic settings. To address the latter question, seroprevalence studies are urgently needed.

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Keywords: WHO; Worldwide; Zika Virus; Updates; GBS; Microcephaly.

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