Title: #Investigation of #Patients Testing Positive for #YellowFever Viral #RNA After #Vaccination During a Mass YF Vacc. Campaign — #Angola, 2016.
Subject: Yellow Fever Outbreak in Angola, vaccination.
Source: US Centers for Disease Control and Prevention (CDC), MMWR Morbidity and Mortality Weekly Report, full page: (LINK). Abstract, edited.
Code: [ ]
Notes from the Field: Investigation of Patients Testing Positive for Yellow Fever Viral RNA After Vaccination During a Mass Yellow Fever Vaccination Campaign — Angola, 2016
Weekly / March 17, 2017 / 66(10);282–283
Format: [ PDF [115 KB] ]
Andrew T. Boyd, MD1,2; Diambi Dombaxe, MD3; Rosa Moreira, MD3; M.S. Oliveira, MD4; Eusebio Manuel, MD4; Carlos Navarro Colorado, MD, PhD2; Tatiana M. Lanzieri, MD5
1Epidemic Intelligence Service, CDC; 2Division of Global Health Protection, Center for Global Health, CDC; 3Angola Field Epidemiology and Laboratory Training Program, Ministry of Health, Republic of Angola; 4Ministry of Health, Republic of Angola; 5Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, CDC.
Corresponding author: Andrew T. Boyd, firstname.lastname@example.org, 404-498-0024.
Suggested citation for this article: Boyd AT, Dombaxe D, Moreira R, et al. Notes from the Field: Investigation of Patients Testing Positive for Yellow Fever Viral RNA After Vaccination During a Mass Yellow Fever Vaccination Campaign — Angola, 2016. MMWR Morb Mortal Wkly Rep 2017;66:282–283. DOI: http://dx.doi.org/10.15585/mmwr.mm6610a5.
The yellow fever outbreak declared in Angola in January 2016 soon became the largest recorded yellow fever outbreak in the country’s history. In response, the Angola Ministry of Health, supported by the World Health Organization (WHO), conducted mass yellow fever vaccination campaigns beginning in February 2016 for all persons aged ≥6 months. By June 2016, a total of 11.6 million yellow fever vaccine doses had been distributed among a national population of 25 million. Because of the urgency of distributing vaccine to stop the outbreak, surveillance for cases of yellow fever after vaccination and serious adverse events after immunization (AEFIs) was not implemented. However, CDC and the Angola Field Epidemiology and Laboratory Training Program conducted an investigation of patients with a history of yellow fever vaccination and symptoms of yellow fever disease whose specimens tested positive for yellow fever viral RNA by reverse transcription–polymerase chain reaction (RT-PCR) to assess whether such cases could represent vaccine failure or AEFIs.
Keywords: US CDC; Updates; Abstracts; Yellow Fever; Vaccines; Angola.