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#Analysis of recent #scientific #information on #avian #influenza A(#H7N9) virus - 10 February 2017 (@WHO, edited)

  Title : #Analysis of recent #scientific #information on #avian #influenza A(#H7N9) virus - 10 February 2017. Subject : Avian Influenza, ...

16 Feb 2017

#H7N9 #Influenza–#situation #update as of 15 February 2017 (#FAO, edited)

 

Title: #H7N9 #Influenza–#situation #update as of 15 February 2017.

Subject: Avian Influenza, H7N9 subtype, poultry enzootic and human epidemic in China.

Source: Food and Agriculture Organization (FAO), full page: (LINK).

Code: [     ]

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H7N9 Influenza - situation update as of 15 February 2017

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The next update will be issued on 22 February 2017

 

Disclaimer

Information provided herein is current as of the date of issue. Information added or changed since the last H7N9 situation update appears in red. Human cases are depicted in the geographic location of their report. For some cases, exposure may have occurred in one geographic location but reported in another. For cases with unknown onset date, reporting date was used instead. FAO compiles information drawn from multiple national (Ministries of Agriculture or Livestock, Ministries of Health, Provincial Government websites; Centers for Disease Prevention and Control [CDC]) and international sources (World Health Organization [WHO], World Organisation for Animal Health [OIE]) as well as peer-reviewed scientific articles. FAO makes every effort to ensure, but does not guarantee, accuracy, completeness or authenticity of the information. The designation employed and the presentation of material on the map do not imply the expression of any opinion whatsoever on the part of FAO concerning the legal or constitutional status of any country, territory or sea area, or concerning the delimitation of frontiers.

 

Overview

  • Situation:
    • Influenza A(H7N9) virus with pandemic potential.
  • Country:
    • China; three human cases originated in China and were reported in Malaysia (1) and Canada (2).
  • Number of human cases:
    • 1174 confirmed; 417 deaths (since February 2013)
  • Provinces/municipalities:
    • [China]
      • Beijing,
      • Shanghai and
      • Tianjin municipalities;
      • Anhui;
      • Fujian;
      • Guangdong;
      • Hubei and
      • Liaoning provinces;
      • Henan;
      • Hunan;
      • Jiangsu;
      • Jiangxi;
      • Shandong;
      • Zhejiang;
      • Guizhou;
      • Jilin;
      • Qinghai;
      • Hubei;
      • Sichuan;
      • Hong Kong SAR;
      • Macao SAR,
      • Guangxi,
      • Ningxia Hui and
      • Xinjiang Uyghur Autonomous Regions;
    • [Taiwan] Province of China;
    • [Malaysia]
      • Sabah;
    • [Canada]
      • British Columbia.
  • Animal/environmental findings:
    • over 2,000 virological samples from the environment, chickens, pigeons, ducks and a tree sparrow tested positive; positives mainly from live bird markets, vendors and some commercial or breeding farms.
  • FAO actions:
    • liaise with China and partners, monitor situation, monitor virus evolution, conduct market chain analysis, risk assessment, surveillance guidance and communication.

 

Map. Human cases and positive findings in birds or the environment

Human cases and positive findings in birds or the environment

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|—Click on image to enlarge –|

Note:  Human cases are depicted in the geographic location where they were reported; for some cases, exposure may have occurred in a different geographic location. Precise location of 14 human cases in Anhui (5), Beijing (1), Hunan (4), Hubei (3), Jiangsu (11), Sichuan (2) and Zhejiang (1) Provinces are currently not known, these cases are therefore not shown on the map.

 

Situation update

  • Animals
    • 14 February:
      • MoA published the results of the national animal H7N9 surveillance for the month of January.
      • 102,123 serum and 55,392 virological samples were collected from 6,589 locations in 26 provinces.
      • 26 virology samples tested positive for H7N9 virus in Guangdong (20 chickens from 12 markets in 5 cities), Guizhou (2 chickens from 2 markets), Hunan (1 chicken and 1 duck from a farm) and Jiangsu (1 chicken from a market) Provinces.
      • In addition, 33 serum samples tested positive for H7 antibodies in Guangdong (21 chickens from 4 markets and 1 household) and Shandong (12 chickens from 3 farms) [reference].
    • 12 February, Sichuan:
      • Suining City authorities closed 280 live poultry trading venues after four human cases were reported in the city in one month [reference].
    • 11 February, Zhejiang:
      • All live poultry markets in the province have been closed.
      • No information was communicated on the duration of the closure [reference].
    • 10 February, Guangdong:
      • Yingde City CDC reported the detection of H7N9 virus in two samples collected from two stalls in a market [reference].
      • Guangzhou City announced the temporary closure of all poultry markets in the city center from 16 to 28 February.
      • Since December 2016, all 11 districts of the city have detected H7N9 virus in poultry markets [reference].
    • 6 February, Hunan:
      • Hunan Provincial Bureau of Animal Husbandry and Fisheries informed that since January 2017, the province collected 6,606 virological and 8,923 serological samples.
      • Virus was found in a wholesale market in Changsha City.
      • The market was closed and is expected to reopen on 13 February after disinfection is completed [reference].
      • On 9 February, the disease control department also reported 23 positive samples in Yueyang City (out of 39 collected) during their environmental monitoring [reference].
  • Humans
    • Since the last update (8 February 2017), 59 new human cases have been reported in:
      • Zhejiang (13),
      • Jiangsu (10),
      • Anhui (6),
      • Fujian (5),
      • Guangdong (4),
      • Hubei (4),
      • Hunan (4),
      • Sichuan (4),
      • Jiangxi (3),
      • Beijing (2),
      • Henan (2),
      • Shanghai (1) and
      • Yunnan (1).
    • For detailed information on human cases, please refer to WHO's Disease Outbreak News.

 

Figure 1. Number of positive virological samples from birds or the environment, by province and origin as of 15 February 2017

Number of positive virological samples from birds or the environment, by province* and origin

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|—Click on image to enlarge –|

 

Figure 2. Number of officially reported human cases since February 2013 as of 15 February 2017

Number of officially reported human cases since February 2013

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|—Click on image to enlarge –|

 

Figure 3. Incidence of officially reported human cases by month, based on onset date as of 15 February 2017

Incidence of officially reported human cases by week, based on onset date

|—Click on image to enlarge –|

Note: For cases with unknown onset dates from wave 1 (n=7), wave 2 (n=2), wave 3 (n=146), wave 4 (n= 27) and wave 5 (n=262) reporting dates were used instead.

 

Publications

  • In addition to the surveillance findings by MoA and MoH, 1,728 virologically positive samples have also been reported in 12 peer-reviewed articles (1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12).
    • A total of 71,920 samples have been collected in these studies since April 2013, of which 1,728 (2.4%) were positive for H7N9 (1,215 environmental samples, 501 chickens, 1 goose and 1 tree sparrow).
  • A human serological survey assessed the prevalence of antibodies to H7N9 virus in the early stages of the epidemic in China (from March 2013 to May 2014).
    • Hemagglutination inhibition (HI) was used as a first screening test and positive samples were confirmed by modified microneutralization (MN) assay.
    • Among the general population sera (n=1,480), none were seropositive.
    • Among poultry worker sera (n=1,866), 28 were positive by HI (of which two were positive by MN).
    • Among 61 sera from healthcare and 117 from non-healthcare contacts, five were positive by HI but all were negative by MN [reference].

 

FAO’s support to countries

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Keywords: FAO; Updates; H7N9; Avian Influenza; Human; China; Poultry.

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