Title: #China, an highly pathogenic #H7N9 #avian #influenza #variant has been isolated from #human cases.
Subject: Avian Influenza, H7N9 subtype, multi-basic cleavage site (making transition from low pathogenic to highly pathogenic in poultry) in the hemagglutinin found in human isolates.
Source: Local Media, via Xinhua, full page: (LINK). Article in Chinese, edited.
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#China, an highly pathogenic #H7N9 #avian #influenza #variant has been isolated from #human cases
2017-02-19 16:32:00 Source: China News Network
Guangzhou, Feb. 19 (Xinhuanet) - In January 2017, the Center conducted a gene sequencing analysis of two strains of H7N9-infected patients, and found that the two viruses possessed a multi-basic cleavage site in the hemagglutinin gene, suggesting that the virus mutates into a highly pathogenic virus against birds.
Guangdong Provincial Center for Disease Control and Prevention experts to judge and communicate with the relevant experts in the agricultural sector that, according to the results of the virus sequence analysis, the virus has not showed changes in the clinical course of human infection, or virulence or the ability to spread efficiently human to human related to this mutation.
Two cases of disease before the incidence of bird exposure history, and in the exposure of poultry birds have occurred in the phenomenon of death. At present, a case has been cured, another case is still in treatment. All the 105 cases of close contact after two weeks of medical observation, were not fever, cough and other symptoms.
H7N9 virus is a influenza virus, one of its main features is prone to gene reassignment and mutation. Some mutations may lead to the virus on the human appeal, virulence and interpersonal communication capacity enhancement, so the virus mutation has been widely concerned at home and abroad.
It is understood that the agricultural sector laboratory also from Guangdong, four poultry specimens found similar to the variation of the virus. China Healthcare System will work with the agricultural sector to jointly study the source and scope of the variability virus and continue to strengthen the monitoring of the H7N9 virus and discover any possible variability.
The results have been communicated to the World Health Organization.
Keywords: China; Avian Influenza; H7N9; Human; Poultry; Guangdong.