22 Jan 2013

Mucormycosis cerebral arteritis mimicking a flare in ANCA-associated vasculitis (The Lancet Infect Dis., extract, edited)

[Source: The Lancet Infectious Diseases, full page: (LINK). Extract, edited.]

The Lancet Infectious Diseases, Volume 13, Issue 2, Page 182, February 2013

doi:10.1016/S1473-3099(12)70143-3

Mucormycosis cerebral arteritis mimicking a flare in ANCA-associated vasculitis

Original Text

Mathieu Royer MD a, Pascale Cervera MD c, Prof André Kahan MD b, Prof Charles-Joël Menkès MD b, Dr Xavier Puéchal MD a b

a National Referral Center for Rare Systemic Auto-immune Diseases, Necrotizing Vasculitides, AP-HP Cochin Hospital, Paris Descartes University, Paris, France; b Department of Rheumatology, AP-HP Cochin Hospital, Paris Descartes University, Paris, France; c Department of Pathology, AP-HP Saint-Antoine Hospital, Pierre & Marie Curie University, Paris, France

Corresspondence to: Dr Xavier Puéchal, National Referral Center for Rare Systemic Auto-immune Diseases, Necrotising Vasculitides, Cochin Hospital, 27 rue du Faubourg Saint-Jacques, 75679 Paris Cedex 14, France

 

A 65-year-old man presented with type 2 diabetes and a relapsing antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. He was admitted for a suspected new vasculitis flare with the onset of frontal headache. Brain CT and MRI showed sinusitis and right hemispherical recent ischaemic lesions. The patient developed left hemiplegia and died. Autopsy showed multiple areas of right hemispherical brain infarctions and a segmental destruction of the right middle cerebral artery wall by an ab ...

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