[Source: World Health Organization, full PDF document: (LINK). Edited.]
Influenza at the human-animal interface - Summary and assessment as of 16 January 2013
Human infection with avian influenza A(H5N1) viruses and associated animal health events
From 2003 through 16 January 2013, 610 laboratory-confirmed human cases with avian influenza A(H5N1) virus infection have been officially reported to WHO from 15 countries, of which 360 died.
Since the last update on 17 December 2012, no new laboratory-confirmed human cases with influenza A(H5N1) virus infection were reported to WHO.
Recent poultry outbreaks in Indonesia have been attributed to influenza virus A(H5N1) clade 184.108.40.206. This clade has not been previously detected in Indonesia, although it has been circulating for some years in poultry and has been isolated from a few human cases with H5N1 infection in other countries.
Any time influenza viruses are circulating in poultry there is a risk of sporadic infections or small clusters of human cases.
Based on current information, the public health risk from the H5N1 virus of the 220.127.116.11 clade (e.g. pathogenicity, transmissibility in humans) does not seem to be different from the public health risk associated with other H5N1 virus clades.
Public health risk assessment of avian influenza A(H5N1) viruses: The public health risk remains unchanged.
Human infection with other non-human influenza viruses
A(H3N2) variant virus infection
No new human cases of influenza A(H3N2)v infection were reported from the United States of America (USA).
Overall public health risk assessment of the influenza A(H3N2)v viruses: Further human cases and small clusters may be expected as this virus is circulating in the swine population in the USA. Close monitoring of the situation is warranted.
Animal outbreaks with high pathogenic avian influenza viruses with potential public health impact
Overall, official reports of animal influenza outbreaks have increased over the past months (http://www.oie.int/wahis_2/public/wahid.php/Diseaseinformation/WI ). This seasonal pattern is expected with the onset of winter in the northern hemisphere.
In Mexico, new influenza A(H7N3) outbreaks in poultry were reported. During last summer (2012) in Mexico, 2 cases of human infection with A(H7N3) were associated with a similar outbreak in poultry. These cases were mild, with conjunctivitis as the main clinical sign (http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6136a4.htm ). This highlights the need for countries experiencing outbreaks of influenza virus infection in animals to raise disease awareness and implement appropriate biosafety measures to protect people working with or living nearby infected and potentially infected animals. Collaboration with animal health partners is necessary to optimally control this disease in animals and decrease risks to public health.
Due to the nature of constant evolving of influenza viruses, WHO continues to stress the importance of global monitoring of influenza viruses and recommends all Member States to strengthen routine influenza surveillance. All human infections with non-seasonal influenza viruses are reportable to WHO under IHR (2005).
- WHO human-animal interface web page http://www.who.int/influenza/human_animal_interface/en/
- Cumulative Number of Confirmed Human Cases of Avian Influenza A/(H5N1) Reported to WHO http://www.who.int/influenza/human_animal_interface/EN_GIP_LatestCumulativeNumberH5N1cases.pdf
- H5N1 avian influenza: timeline of major events http://www.who.int/influenza/human_animal_interface/avian_influenza/H5N1_avian_influenza_update.pdf
- World Organisation of Animal Health (OIE) web page: Web portal on Avian Influenza http://www.oie.int/animal-health-in-the-world/web-portal-on-avian-influenza/
- Food and Agriculture Organization of the UN (FAO) webpage: Avian Influenza http://www.fao.org/avianflu/en/index.html
- OFFLU http://www.offlu.net/index.html