12/04/2012

ALGORITHM FOR INVESTIGATION AND MANAGEMENT OF POSSIBLE CASES OF SEVERE ACUTE RESPIRATORY ILLNESS ASSOCIATED WITH A NOVEL CORONAVIRUS (HPA UK, December 4 2012, edited)

[Source: Health Protection Agency, United Kingdom, full PDF document: (LINK). Edited.]

HPS CASE MANAGEMENT ALGORITHM Version No. case_v9  03/12/2012 / For all email contact with HPS Colindale, please use respiratory.lead@hpa.org.uk

ALGORITHM FOR INVESTIGATION AND MANAGEMENT OF POSSIBLE CASES OF SEVERE ACUTE RESPIRATORY ILLNESS ASSOCIATED WITH A NOVEL CORONAVIRUS

 

POSSIBLE CASE

PATIENT UNDER INVESTIGATION

  • Any person with severe acute respiratory infection;
  • Symptoms of fever (≥ 38⁰C) or history of fever and cough
    • AND
      • With evidence of pulmonary parenchymal disease (eg. pneumonia or Acute Respiratory Distress Syndrome (ARDS)) based on clinical  or radiological evidence)
    • AND
  • Not explained by any other infection or aetiology (1)
    • AND EITHER
      • History of travel to or residence in an area(2) where infection with novel coronavirus 2012 has recently been reported or where  transmission could have occurred in the ten days before onset of illness
        • OR
      • Healthcare worker based in ICU caring for patients with severe acute respiratory infection
        • OR
      • Close contact (i.e. prolonged face-to-face contact) during the ten days before onset of illness with a confirmed case of novel  coronavirus infection while the case was ill

OR

  • CLUSTER(3)
    • Two or more cases of severe acute  respiratory infection requiring ICU  admission, regardless of history of  travel
      • AND
    • Not explained by any other infection or aetiology (1)

(1) including all clinically indicated tests for community or  hospital acquired pneumonia

(2) as of 03/12/2012:, Bahrain, Iraq, Israel, Jordan, Kingdom of  Saudi Arabia, Kuwait, Lebanon, Oman, Qatar, Syria, UAE  and Yemen – see map http://www.un.org/Depts/Cartographic/map/profile/mideastr.pdf

(3) Cluster is defined as two or more cases within a specific closed setting (eg. classroom, workplace, household, hospital, other residential institution), developing symptoms within the same two week period

 

MEETS POSSIBLE CASE DEFINITION

 

REGIONAL LAB TEST NEGATIVE FOR NOVEL CORONAVIRUS -----> DISCARD

 

REGIONAL LAB TEST POSITIVE FOR NOVEL CORONAVIRUS

  • Ensure HPU is notified
  • HPU informs HPS Colindale by email
  • HPU collates list of contacts* using contact line list – email to HPS Colindale
  • ADDITIONALLY FOLLOW “CLOSE CONTACT OF A CASE POSITIVE FOR NOVEL CORONAVIRUS FOLLOW UP ALGORITHM”

 

BASELINE

 

FOLLOW UP

______________________________

! Baseline clotted blood sample should be taken asap and ideally no later than 7 days after symptom onset.  Followup sample should be taken at least 14 days after the baseline sample, or 28 days after illness onset if a sample couldn’t be taken when  case was symptomatic.

(*) Contact definitions (from date of illness onset in index case and throughout their symptomatic period):

  • Health and social care workers: worker who provided direct clinical or personal care or examination of a symptomatic case positive for novel coronavirus or within close vicinity of an aerosol generating  procedure AND who were not wearing full personal protective equipment (PPE***) at the time.
  • Household or close contact: any person who has had prolonged face-to-face contact (>15 minutes) with a symptomatic case positive for novel coronavirus in a household or other closed setting.

(**) Full PPE is defined as correctly fitted high filtration respirator (FFP3), gown, gloves and eye protection.

 

-

--------