20 Apr 2014

Saudi Arabia MoH reported thirteen new MERS-CoV cases (April 20 2014)

[Source: Saudi Arabia Ministry of Health, full page: (LINK). Automatic translation from Arabic.]

Saudi Arabia MoH reported thirteen new MERS-CoV cases

(April 20 2014)

In the context of the work of epidemiological investigation and ongoing follow-up carried out by the Ministry of Health for the novel coronavirus that causes Middle East Respiratory Syndrome (MERS CoV) Ministry announces thirteen new cases of infection in the Kingdom.

  1. a Jeddah resident, 49 years old, passed away.
  2. a Jeddah resident, 57 years, currently in intensive care.
  3. a Jeddah resident, 32 years old, in stable condition.
  4. a Jeddah resident, 53 years old, in stable condition.
  5. a Jeddah resident, 54 years old, in stable condition. 
  6. a Jeddah resident, 23 years old, asymptomatic.
  7. a Jeddah health care worker, 37 years old, in stable condition.   
  8. a Riyadh resident, 69 years old, suffering from several chronic diseases, currently in intensive care.
  9. a Riyadh resident, 88 years old, suffering from several chronic diseases, in intensive care.
  10. a Riyadh resident, 57 years old, suffering from several chronic diseases in stable condition.
  11. a Riyadh health care worker, 41 years old, in stable condition.
  12. a Najran resident, 68 years old, suffering from several chronic diseases, passed away.
  13. a Medina resident, 68 years old, suffering from several chronic diseases, passed away.

In this context, and in order from the Ministry of Health to provide all members of the community, the media and social networking guidelines of health and medical advice on HIV corona virus that causes AIDS Middle East, respiratory, and inform them of the developments around it, they invite everyone to access the link on the disease through the Ministry's website www.moh.gov.sa / Coronanew , or communicate via toll-free phone 8002494444 or 937 center or through a link saudimoh @ Twitter wishing for all health and safety.

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Saudi Arabia announces jump in new cases of deadly Mers virus (Straits Times Interactive, April 20 2014)

[Source: Straits Times, full page: (LINK).]

Saudi Arabia announces jump in new cases of deadly Mers virus

April 20, 2014 9:19 PM

RIYADH (REUTERS) - Saudi Arabia has confirmed seven new cases of Middle East Respiratory Syndrome (Mers), adding up to 36 infections in five days, a sudden increase of a disease that kills about a third of the people infected and has no cure.

(…)

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Saudi Arabia Health Minister of MERS-CoV current situation (April 20 2014, edited)

[Source: Saudi Arabia Ministry of Health, full page: (LINK). Automatic translation from Arabic.]

Saudi Arabia Health Minister of MERS-CoV current situation

(April 20 2014)

Revealed the Minister of Health Dr. Abdullah Al-Rabiah recording 13 new cases of novel Coronavirus included 7 cases in Jeddah and 4 in Riyadh and one in each of the Medina and Najran added to the 244 case the former announced in all regions of the Kingdom and His Excellency stressed that the ministry is doing Jhdhalahtwae virus and stressing the readiness Ministry of Hajj and Umrah seasons Bmaldiha of extensive experience as a scientific reference has become a medicine in the crowds.

This came during a press conference held by His Excellency this afternoon in the presence of members of the National Scientific Committee for Infectious Diseases and embryos national infection control,

His Excellency the National Scientific Committee for Infectious Diseases confirmed that the actions taken in the health facilities in line with international standards and national infection control and do not need to additions to the readiness and availability All hardware and supplies needed to deal with the cases.

He assured His Excellency that did not record any case in schools and thankfully it is what I consider a positive sign that the cases recorded amid health practitioners began less, as the mortality rate decreased from 60% at the beginning of the emergence of the virus to 35% last week to fall to 32% today.

He predicted Ma'aleh high number of cases registered in the coming weeks due to increased epidemiological investigation, noting that he was examined 20 thousand cases, which underlines the size of the work being done by the Ministry of Health, announced Ma'aleh that National Scientific Committee for Infectious Diseases and the consent of all its members, who represent most of the state ministries and health sectors and sector will hold a private meeting daily to see the developments of the virus.

He noted that the ministry has called 22 experts from the World Health Organization and the Centers for controlling epidemics in Europe, America and East Asia, and experts from the Gulf Cooperation Council for the meeting this weekend at the headquarters of the Ministry of Health to view these cases and come up with new recommendations, as the Ministry of Health called the world's experts and national experts, as well as 5 companies called global manufacturer of vaccines for cooperation with the Ministry of Health for research on the possibility of manufacturing the vaccine through the information known about the virus.

The embryos showed the national infectious diseases that the total cases registered in the province of Jeddah reached 64 cases, of which 12 died registered cases accounted for 18%, which is lower than the overall rate of mortality, which is 32%.

The pant Committee that he and the interest of the Ministry of Health to provide all members of the community, the media and social networking guidelines of health and medical advice on HIV corona virus that causes AIDS Middle East respiratory, and inform them of the developments around it, they invite everyone to access the link on the disease through the Ministry's website www .moh.gov.sa / coronanew, or communicate via toll-free phone 8002494444 or 937 center, or through a Twitter account in the ministry saudimoh @, and wish for all health and safety.

And about some of the allegations of medical in finding a cure for the disease or eliminate the virus in ambulances committee said it is based on the basis of purely scientific in dealing with the cases, and that there is no scientific evidence for this information, and we deal with any scientific study or scientific research arbitrator according to scientific standards accepted, we are ready for adoption.

He HE d. Al-Rabiah said the National Committee of Scientific Infectious Diseases includes members and consultants for Infectious Diseases and family medicine and community and public health of all health authorities in the Kingdom which the Ministries of Defense, the National Guard, Interior, Education, and Health and the Faculty of Medicine at King Saud University and King Faisal Specialist Hospital and Saudi Aramco, which approved the policy preventive pursued by the Ministry of Health.

The Commission stated that there is a difference to the Ministry of Health is working around the clock, and the procedures for infection control and sterilization places and complete the necessary procedures for infection control.

And demonstrated Committee that there had been cases in the sectors of health following a Ministries of Defense, the National Guard, Interior, Health, as well as the private sector and university hospitals, and Saudi Aramco, which reported a Ministry of Health Hospitals 103 state hospitals and the Ministry of Defense of 46 cases, the hospitals and the Ministry of National Guard 30 state hospitals Security Forces 6 and university hospitals 6 and hospitals Aramco 14 cases and hospitals private health sector 26 cases and King Faisal Specialist Hospital in Riyadh and Jeddah number of 13 cases since the onset of the disease in 2012, bringing the total number of cases, 244 cases, with reference to the cases recorded in the hospitals of the Ministry of Health include patients in addition to the contacts of positive cases of both hospitals and the Ministry of Health, hospitals or other sectors.

And confirmed the National Scientific Committee for Infectious Diseases that the disease has no vaccine or preventive treatment of qualitative and unknown source of contagion is not known how infection is transmitted from one person to another until now. The research is still ongoing with regard to the basic knowledge of the source of infection, where samples are taken in several regions of the Kingdom and it was up to the stage of the epidemic as the Emergency Committee of the World Health Organization, health is authorized to announce it.

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Middle East respiratory syndrome coronavirus (MERS-CoV) – update (WHO, April 20 2014, edited)

[Source: World Health Organization, full page: (LINK). Edited.]

Middle East respiratory syndrome coronavirus (MERS-CoV) – update

20 April 2014

On 18 April 2014, the Ministry of Health of Greece reported one laboratory-confirmed case of infection with Middle East respiratory syndrome coronavirus (MERS-CoV).

 

The following details were provided to WHO by the Ministry of Health, Greece, on 18 April 2014:

  • The patient is a 69-year old male Greek citizen residing in Jeddah, Saudi Arabia, who travelled back to Greece on 17 April.
    • While in Jeddah, the patient consulted a hospital on 8 and 10 April for a febrile illness with diarrhoea, and was given a probable diagnosis of typhoid fever.
    • Of note, he regularly visited his wife who was hospitalised from 31 March to 5 April in the same hospital for a confirmed typhoid fever.
    • The patient sought medical care upon arrival in Greece on 17 April.
    • The evaluation revealed a bilateral pneumonia and the diagnosis of MERS-CoV infection was made at the National Reference Laboratory for Influenza.
    • The patient is in stable condition and is receiving appropriate treatment.

This is the first case of MERS-CoV infection in the country.

Individuals who had close contacts with the case in the plane, the hospital in Greece and in the community have been identified and are being followed up.

So far, none of the contacts became ill.

Hellenic health authorities issued a press release to inform the population and informed all Greek hospitals on measures that need be taken to identify suspect patients and implement appropriate preventive measures.

Globally, from September 2012 to date, WHO has been informed of a total of 250 laboratory-confirmed cases of infection with MERS-CoV, including 93 deaths.

 

WHO advice

Based on the current situation and available information, WHO encourages all Member States to continue their surveillance for severe acute respiratory infections (SARI) and to carefully review any unusual patterns.

Infection prevention and control measures are critical to prevent the possible spread of MERS-CoV in health care facilities. Health-care facilities that provide for patients suspected or confirmed to be infected with MERS-CoV infection should take appropriate measures to decrease the risk of transmission of the virus from an infected patient to other patients, health-care workers and visitors. Health care workers should be educated, trained and refreshed with skills on infection prevention and control.

It is not always possible to identify patients with MERS-CoV early because some have mild or unusual symptoms. For this reason, it is important that health-care workers apply standard precautions consistently with all patients – regardless of their diagnosis – in all work practices all the time.

Droplet precautions should be added to the standard precautions when providing care to all patients with symptoms of acute respiratory infection.
Contact precautions and eye protection should be added when caring for probable or confirmed cases of MERS-CoV infection. Airborne precautions should be applied when performing aerosol generating procedures.

Patients should be managed as potentially infected when the clinical and epidemiological clues strongly suggest MERS-CoV, even if an initial test on a nasopharyngeal swab is negative. Repeat testing should be done when the initial testing is negative, preferably on specimens from the lower respiratory tract.

Health-care providers are advised to maintain vigilance. Recent travellers returning from the Middle East who develop SARI should be tested for MERS-CoV as advised in the current surveillance recommendations.

All Member States are reminded to promptly assess and notify WHO of any new case of infection with MERS-CoV, along with information about potential exposures that may have resulted in infection and a description of the clinical course. Investigation into the source of exposure should promptly be initiated to identify the mode of exposure, so that further transmission of the virus can be prevented.

People at high risk of severe disease due to MERS-CoV should avoid close contact with animals when visiting farms or barn areas where the virus is known to be potentially circulating. For the general public, when visiting a farm or a barn, general hygiene measures, such as regular hand washing before and after touching animals, avoiding contact with sick animals, and following food hygiene practices, should be adhered to.

WHO does not advise special screening at points of entry with regard to this event nor does it currently recommend the application of any travel or trade restrictions.

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Saudi Arabia reported two fatal cases of MERS-CoV (Xinhua, April 20 2014, edited)

[Source: Xinhua, full page in Arabic: (LINK). Automatic translation.]

Saudi Arabia reported two fatal cases of MERS-CoV

16:23:01 20-04-2014 | Arabic. News. Cn   

Riyadh, April 19, 2014 (Xinhua) The Ministry of Health Saudi Arabia on Saturday reported the deaths of two residents in the Kingdom of Coronavirus that causes Middle East Respiratory Syndrome (MERS), in Jeddah province west of the country.

The ministry said in a statement reported in the (previously) electronic Arabia today that the two deaths are a resident of old (64 years old) and last (44 years), pointing to record five new infections.

And back injuries to three Saudis, including a woman, according to the statement.

The other two cases of injury to people working in the health field at the same age (54 years) does not suffer from the symptoms.

The Ministry of Health announced Friday the discovery of Saudi Arabia six cases infected with Corona in Jeddah, one died, as well as recording a similar number in the Riyadh region belong to three Saudi nationals and three residents.

And the announcement of new cases today, according to the newspaper, the number of cases infected with Corona since its inception in Saudi Arabia in September 2012 to 231 cases of whom 76 died.

The Saudi Health Minister Dr. Abdullah Al-Rabiah said in a press statement that the increasing rate of MERS cases registered in the province of did not reach the stage of the epidemic.

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Guangdong Province reported a new human case of avian influenza H7N9 (DoH, April 20 2014, edited)

[Source: Guangdong Province Department of Health, full page: (LINK). Automatic translation from Chinese.]

Guangdong Province reported a new human case of avian influenza H7N9

2014-04-20 10:01:33   / Ministry of Health and Family Planning Commission 

Guangdong Provincial Health and Family Planning Commission April 20 briefing, Shantou City, reported a new confirmed case of H7N9 avian influenza infection.

The case is a female, 55 years old, [Wang], Shantou City. Confirmed on April 19, currently in critical condition in a Shantou city hospital.

An earlier Shantou City case, confirmed on March 22, has been discharged on April 14;  a Shenzhen case, confirmed on April 1, has been discharged; a Guangzhou City case, confirmed on April 10,  [Luomou] developed septic shock and multiple organ failure, finally passed away on April 15.

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Hong Kong, CHP closely monitors an additional human case of avian influenza A(H7N9) in Mainland (April 20 2014)

[Source: Centre for Health Protection, Hong Kong PRC SAR, full page: (LINK).]

CHP closely monitors an additional human case of avian influenza A(H7N9) in Mainland

The Centre for Health Protection (CHP) of the Department of Health (DH) is closely monitoring, as of yesterday (April 19), an additional human case of avian influenza A(H7N9) in Jiangsu according to the latest report of the Mainland health authorities.

The case involves a woman aged 35 who is currently hospitalised for treatment.

A total of 412 human cases of avian influenza A(H7N9) have been confirmed in the Mainland, including:

  1. Zhejiang (138 cases),
  2. Guangdong (102 cases),
  3. Jiangsu (52 cases),
  4. Shanghai (41 cases),
  5. Fujian (22 cases),
  6. Hunan (21 cases),
  7. Anhui (13 cases),
  8. Jiangxi (six cases),
  9. Beijing (four cases),
  10. Henan (four cases),
  11. Guangxi (three cases),
  12. Shandong (three cases),
  13. Guizhou (one case, imported from Zhejiang),
  14. Hebei (one case) and
  15. Jilin (one case).

(…)

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19 Apr 2014

Research Articles Abstracts–April 19 2014 Issue

[Source: AMEDEO, homepage: (LINK).]

Research Articles Abstracts–April 19 2014 Issue

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This week’s Abstracts:

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  • BMJ
  • Cell
    • MILLER MS, Palese P
  • J Gen Virol
    • EL-SHESHENY R, Kandeil A, Bagato O, Maatouq AM, et al
      • Molecular characterization of avian influenza H5N1 virus in Egypt and the emergence of a novel endemic sub-clade.
  • J Infect Dis
    • BIGGERSTAFF M, Jhung MA, Reed C, Fry AM, et al
      • Influenza-like illness, the time to seek healthcare, and influenza antiviral receipt during the 2010-11 influenza season -- United States.
    • LINDEGREN ML, Schaffner W
      • Treatment with Neuraminidase Inhibitors for High Risk Patients with influenza: Why is adherence to antiviral treatment recommendations so low?
  • J Virol
    • REUTHER P, Giese S, Gotz V, Riegger D, et al
      • Phosphorylation of highly conserved serine residues in the influenza A virus nuclear export protein NEP plays a minor role in viral growth in human cells and mice.
    • TAO H, Steel J, Lowen AC
    • CAO S, Jiang J, Li J, Li Y, et al
    • GAO S, Wang S, Cao S, Sun L, et al
      • The characteristics of nucleocytoplasmic transport of H1N1 influenza A viruses nuclear export protein (NEP).
  • PLoS One
    • NTSHOE GM, McAnerney JM, Tempia S, Blumberg L, et al
      • Influenza Epidemiology and Vaccine Effectiveness among Patients with Influenza-Like Illness, Viral Watch Sentinel Sites, South Africa, 2005-2009.
      • Correction: Pretreatment of Epithelial Cells with Live Streptococcus pneumoniae Has No Detectable Effect on Influenza A Virus Replication In Vitro.
    • MESQUITA M, Resende P, Marttorelli A, Machado V, et al
      • Detection of the Influenza A(H1N1)pdm09 Virus Carrying the K-15E, P83S and Q293H Mutations in Patients Who Have Undergone Bone Marrow Transplant.
    • TONG HH, Lambert G, Li YX, Thurman JM, et al
      • Deletion of the Complement C5a Receptor Alleviates the Severity of Acute Pneumococcal Otitis Media following Influenza A Virus Infection in Mice.
      • Correction: identification and chronological analysis of genomic signatures in influenza a viruses.
    • XIE Z, Huang J, Luo S, Xie Z, et al
      • Ultrasensitive electrochemical immunoassay for avian influenza subtype h5 using nanocomposite.
  • Proc Natl Acad Sci U S A
    • CONNARIS H, Govorkova EA, Ligertwood Y, Dutia BM, et al
      • Prevention of influenza by targeting host receptors using engineered proteins.
  • Vaccine
    • LU PJ, O'Halloran A, Ding H, Williams WW, et al
      • National and state-specific estimates of place of influenza vaccination among adult populations - United States, 2011-12 influenza season.
    • NEUHAUS V, Chichester JA, Ebensen T, Schwarz K, et al
      • A new adjuvanted nanoparticle-based H1N1 influenza vaccine induced antigen-specific local mucosal and systemic immune responses after administration into the lung.
    • TABYNOV K, Kydyrbayev Z, Ryskeldinova S, Assanzhanova N, et al
      • Duration of the protective immune response after prime and booster vaccination of yearlings with a live modified cold-adapted viral vaccine against equine influenza.
  • Virology
    • NOISUMDAENG P, Pooruk P, Prasertsopon J, Assanasen S, et al
      • Homosubtypic and heterosubtypic antibodies against highly pathogenic avian influenza H5N1 recombinant proteins in H5N1 survivors and non-H5N1 subjects.
    • KUKOL A, Hughes DJ
      • Large-scale analysis of influenza A virus nucleoprotein sequence conservation reveals potential drug-target sites.
    • KELVIN AA, Degousee N, Banner D, Stefanski E, et al
      • Lack of group X secreted phospholipase A2 increases survival following pandemic H1N1 influenza infection.
    • LU X, Liu F, Zeng H, Sheu T, et al
      • Evaluation of the antigenic relatedness and cross-protective immunity of the neuraminidase between human influenza A (H1N1) virus and highly pathogenic avian influenza A (H5N1) virus.
  • Virus Res
    • METREVELI G, Gao Q, Mena N, Schmolke M, et al
      • The origin of the PB1 segment of swine influenza A virus subtype H1N2 determines viral pathogenicity in mice.

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Coronavirus MERS: décès de deux expatriés en Arabie saoudite (Le Temps d’Algérie, April 19 2014)

[Source: Le Temps d’Algérie, full page: (LINK).]

Coronavirus MERS: décès de deux expatriés en Arabie saoudite

Santé-Coronavirus MERS: décès de deux expatriés en Arabie saoudite. Deux expatriés atteints du coronavirus MERS sont morts à Jeddah, dans l'ouest de l'Arabie saoudite, où cinq autres cas de contamination ont été diagnostiqués, a indiqué samedi le ministère de la Santé.

(…)

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Greece, Ministry of Health update on the imported MERS-CoV case (April 19 2014, edited)

[Source: Ministry of Health of Greece, full page in Greek: (LINK). Automatic translation.]

Greece, Ministry of Health update on the imported MERS-CoV case

April 19, 2014

MINISTRY OF HEALTH / E.K.EP.Y. / PRESS RELEASE

Following the press release of 18/04/2014 KEELPNO, EKEPY inform the patient suffering from viral infection - pneumonia coronavirus ( MERS ), was hospitalized in Special negative pressure units.

The diagnosis was confirmed by the Microbiology Laboratory of the Medical School of Athens University.

The patient's condition is stable.

Updated guidelines for the particular disease, have been sent to all hospitals in E.K.EP.Y. for further alert ( www keelpno . GR ).

HCDCP complete tracing of all contacts of the patient during the voyage from the Arabian peninsula by Greece.

As part of the above process is asked the taxi driver who transported the patient as a traveler from the Airport'' Eleftherios Venizelos'' in Amfialis Keratsinioy between the hours of 14:30 to 16:30 of 04/17/2014, to communicate with K / BUSINESS - KEEL phone: 210 5212054 & 210 5212000.

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